Flora Perini (20 November 1887 – September 1975) was an Italian operatic mezzo-soprano who had a prominent opera career in Europe, South America, and the United States during the first half of the twentieth century. She sang a wide repertoire that encompassed works by verisimo composers like Mascagni, bel canto composers like Rossini and Bellini, the Italian grand operas of Verdi, the German operas of Strauss and Wagner, and the Russian operas of Rimsky-Korsakov. She sang in numerous premieres throughout her career, including creating the role of the Princess in the original 1918 production of Puccini's Suor Angelica.